Arc Institute

@arcinstitute

A full-stack institute for AI and biology research.

Palo Alto, CA

Joined November 2021

Arc Institute
@arcinstitute
15h
Nearly 300 teams have already submitted to the Virtual Cell Challenge leaderboard to see how their initial models rank on this year’s six metrics. Here’s the current standing:
Arc Institute
@arcinstitute
Aug 20
The 2026 Virtual Cell Challenge has begun! Submissions and the leaderboard are now open. This year's task: multi-context generalization and zero-shot prediction. Models will need to predict perturbation responses in cellular contexts with no Challenge-specific training data.
The 2026 Virtual Cell Challenge: predicting perturbation responses in cell contexts a model has...
From arcinstitute.org
Arc Institute
@arcinstitute
Aug 19
Evolution builds genes by recombining domains from existing ones. Innovation Investigator @Roth_Lab and colleagues introduce DESynR, a platform that does this on demand, creating new genes that outperform their natural counterparts in human CAR T cells.
Arc Institute
@arcinstitute
Aug 17
Four years ago, a mystery case led Core Investigator @jvpluv to discover a new diagnosis (ABCD). Today his team published one of the largest clinical surveys of unexplained spinal cord disease to date in @JAMANeuro, finding ABCD in roughly half of patients.
Arc Institute
@arcinstitute
Aug 14
The same method that teaches an LLM which answers people prefer can teach a protein model which sequences are more stable. This is the basis for ProteinDPO, developed by Innovation Investigator @BrianHie, @talaldotpdb, and team.