NIH researchers have gained critical new insight into Köhlmeier-Degos disease, a rare and life-threatening disorder that damages small blood vessels. Read more: bit.ly/4zjRUal.
NIH on X: "NIH researchers have gained critical new insight into Köhlmeier-Degos disease, a rare and life-threatening disorder that damages small blood vessels. Read more: https://t.co/PXIPQckWlC."
x.com/andrewcaravell… highlightsA proposed convergent molecular chain linking senescence, cancer, and chronic infection to a correctable failure of dendritic cell instruction frontiersin.org/journals/immun…
Oh shit we just started studying this too
Important distinction: the paper enrolled 14 patients and links type I + II interferon signaling to clonally restricted cytotoxic T cells. The treatment signal is n=1: better skin, stable neurologic disease on ruxolitinib. Replication is the next gate.
